I run the Virus as a plugin inside Logic and works very smoothly. You can browse, save, edit and load patches quickly. You can twist and twiddle knobs either on the GUI or on the synth itself. It doesn't eat much CPU, since the Virus does all the processing. As you can imagine, it sounds awesome. Oh, and the 'Atomizer' effect is really dope.

The only thing about is this: the plugin allows you to run the Virus on multiple channels simultaneously, so they give you a lot of headroom on each channel so that when they're all summed, you can avoid clipping and distortion. The problem is that the Virus will sound kind of quiet in relation to all the other tracks if your only using one channel. It's easy enough to get around though; I just add a gain booster to the Virus track.

Have fun!